My wife carried a Glock 19 for a couple of years, but SHE never liked how SHE shot it and did not like the lack of a manual safety.

We found her a Beretta 84, which is like a 92 only scaled down for .380 Auto. She loves the de-cocker/safety and can shoot it very well at self-defense distances. It's a bit heavier and longer than the typical "girl" semi-auto in .380, but it works for HER and that's what counts.