depends on the individual gun some shoot the mag ok but almost none shoot them very well. A 22LR bullet will measure .218-.219 and a mag bullet will measure .223-.224 The bore on the six's works best with the smaller bullet whereas for a mag a centerfire 22 barrel will work best which is why high end guns like the FA aren't convertible.
Rod, I have a FA M97 with the interchangeable cylinders. I agree on the accuracy issues with single-six's. I've had two and neither shot the mag cylinder well. Don't know what FA does different, but both my cylinders will shoot equally accurate (very accurate). I haven't checked it, but FA post all their specs for each given model/caliber/barrel length. It may be that FA found a "happy medium" on bore diameter for the 22lr/mag.
