I was wondering why DT doesn't list that as a plus p load myself. I have my gun set up for 45 Super with a 24lb recoil spring and fully supported barrel, so I should be ok either way. But, at that spring weight I'm getting some ftw issues with those loads. I believe as Reflex264 says, I would be better served with a 19 or 20lb spring.
Not sure what the result of that load would be on a bigger deer shot in the shoulder, but I promise to try to find out. ...