I started with the T/C platforms for all the available handgun & rifle cartridges. If it is a handgun caliber my first choice is the 41 mag and it does a great job on deer. True it is a lot easier to buy ammo and components in the 44 mag. In the T/C's I enjoy the extra range that the 7-30 Waters gives me and is very pleasant and accurate to shoot but I have several rifle calibers also that consist of 30 Herret, 7mm-08, & 308 to name just a few that handle nicely in a single shot handgun.