FWIW, I do not have a 460, only a 454. But in my testing with the 460 Rowland with various 45 ACP bullets, I saw something that really hit home. When you use a bullet that is designed for much lower speeds, you might have unintended conseqences. Like an expanding bullet that literally gets turned inside out. This might work for you and your game and shot presentation, but I think it worth understanding.

Like you are asking here, I also like to ask the maker of the bullet what the design velocity envelope for a particular bullet will be, if not found on their website. Hornady lists a lot of theirs, if you dig around on their web site. Barnes takes a day or five to get back to an email, but they always answer.

Craig