A semi is not the ultimate hunting handgun. With that said, they do make a fine choice. I pack a Sig 1911 5" in 45 Super. I prefer it over the 10mm due to greater bore diameter. I run my 200 gr loads at 1285 fps with Power Pistol. They group 1" at 25 yards. I personally would never consider a 460 Rowland over a 45 Super.

My choice of hunting handgun is a Ruger Hunter SBH in 45 Colt. It is a very fine weapon.