I like the .45 Super myself, some of my favorite handloads are a 255gr SWC Keith style at 1,100 fps for a general purpose load, a 250gr Hornady XTP at 1,300 fps does well and expands nicely or a 255gr BT WFNGC at 1,200-1,300 fps when you want speed and a wide meplat.

I've ran 300gr LFNGC's to over 1150 fps in the .45 Super too, from a 5" comped Glock. You can push the .45 ACP bullets fast, real fast really but that's not a good idea when you've got tougher .45 Colt style JHP's and hardcasts that will serve the purpose better.

Can't really say much about the 10mm, I've had several and didn't think that much of them, but some love them. I like the Super because you get bigger, heavier bullets at a good speed, and with a well supported (and comped) barrel it can mimic the 460 Rowland level loads.