As a hunter education instructor I speak with many handgun hunters about their experiences. The .357 magnum 125 grain load is great for wounding and losing deer. The 140 grain or heavier loads are good killers. Remember that the 125 grain load was developed as an antipersonnel load and works well. Humans and deer react differently to gunshots.

I can do all things through Christ which strengtheneth me. Phil. 4:13