I have been hunting with a .41 of some sort for about 10 years now. All of the guns I've had/have have done well with the 210 grain xtp. I've pushed it with h110, AA#9, and even Blue dot. Somewwhere just below published maximums tends to get the best accuracy in my experience. Right now I'm using 21 grains of h110 and CCI large pistol(not magnum!) Primers. Your mileage may vary but it is a place to start. I think you will be pleased with your new hunting tool. Happy shooting.