I emailed Ruger and this was the reply: US SAAMI 45acp may swell in the chamber, if this is reloaded ammo the cases may split. We do not recommend using reloading ammo in any of our firearms.. Ruger will not be responsible for the operation of or damage to your firearm caused by reloaded ammunition, or ammunition that is not manufactured to SAAMI (US) or CIP (European) Standards.
This will definitely not be a gun for my collection.

I can do all things through Christ which strengtheneth me. Phil. 4:13