i'd go with the 454, not much out kills better than a 454 with a heavy swift a frame. better component availability. for dangerous game there's much better bullet selection and they're cheaper. you'll never notice the diameter difference and a 400gr 480 vs 360gr hardcast 45 is a moot point as well imho. better trajectory and the recoil argument is moot if ya reload. i have lots of loads my little 95lb daughter shoots out of my 454. then again, she shoots my 6.5"smith 500 as well.