I recently had a similar dilemma. Choosing between the 454ruger and the 460SW. I ended up choosing the 460SW because it would also shoot the 454 and 45lc. I am glad I did because shooting the 454 out of the SW x frame feels like shooting a hot.357 and its actually enjoyable.
When I considered the .480 it seemed to me to be a jacked up .44 mag but with less available ammo and ammo options. I have never shot a .480 though.
I also took into account that the resale value, should I get into the horrible situation where I would have to liquidate some guns, would probably be much higher with the .460 because of the availability shoot the other rounds then the .480.
People rarely talk about that side of buying guns?