If yer limited to store bought, I would recommend these guys:

http://shop.reedsammo.com/45-Long-Colt-T-C-Ruger-Loads_c72.htm

I like the 250 XTP in the 45 Colt. Easy on the shooter and hard on deer. If you are going to hunt big bear or hogs you might try a heavier slug, but the 250 XTP is a good one for most game on this continent.