The Super is an absolutely fantastic cartridge, wish it were more popular. I've loaded it from "mild" to equaling the 460 Rowland and had good luck with it in a .45 ACP convertible .45 Colt Blackhawk (and comped G21). At mid range I'm sure it would be okay in a Smith, I prefer the cartridge to keep 250/275's in the 1050-1100 range, 230's in the 1150-1200 range, 200's in the 1250-1300 range and 185's in the 1350+ range, any more and it seems to really beat on the gun pretty hard.