James,

I run the 250's to 1,780 fps out of my 45 Colt Carbine. While that is faster than the Hornady recommended top end velocity of 1600 fps, they are pretty close to the 1600 fps at impact. They are very effective at those speeds on deer, usually leaving golf ball diameter exits. They've always held together well and exited deer. I probably wouldn't want to shoot really large game with them, but for black bear or deer I wouldn't hesitate. Out of the rifle I should shoot the 240 XTP Mag but I have so many of the 250's loaded up already, and they shoot less than 1 MOA.

Eric.