I've watched some of the YouTube videos of the Extreme Penetrator Bullet in the 500 S&W. They were impressive, but it was a 500 too. I used the 350 gr Extreme Penetrator Bullet out of my SSK Encore Barrel in 500 S&W loaded from Underwood on a big boar that I shot. Tissue damage seemed very similar to a HC to me..Caliber size, but really nothing to get excited about