I just read too many articles back years ago in The Sixgunner, where...he was using a Glock 10mm, and he had to shoot everything multiple times and he could even get pass throughs on Spanish Goats with his 10mm
I will tell you with certainty, that no PH wants you to shoot once (even when rifle hunting). That said, if you need 15, you have a real problem!
Here's one of my 10mm kills.