Why would you not use the 221 fireball?
Otherwise, id use the same loads you would hunt deer with in the 44. ANY load in 44 would work on a coyote. but...... a good smokin 180gr would surely do the trick.
You know, after giving it a bit of thought, I think the first pistol that needs to see some action is my 327. Last season, I tried to make a shot on a coyote that wandered in close but struck the hay bale I was hiding behind because I didn't clear the muzzle. I just
can't be 0-1 with a pistol.
That said, the 44 will give me an excuse to get another pound of H110 or W296 before someone buys it up.