For my Rugers, I have fallen in love with the Ragged Hole. (No, not my X-Wife) It's faster that a dot and so much nicer to carry.
My 45/70 and .357 Max 'Tenders are topped with 1.25-4's cause I don't need to see much further than that, a 2x would do as well.
My .22 Mag and 7-30 Waters Hunter have 3-9x rifle scopes to get a better sight picture.
My HMR and Hornet wear 6.5-20x50mm varmint rifle scopes so I can see the little critters.
My 12" .44 Mag has a Red/Green Dot, I prefer the green myself.
Every sight(s) for any purpose