I think I'd like a quick follow up shot for anything that bites & is upset w/me. That situation IMHO begs for a DA. I prefer SA's & don't even own a big bore DA. I'd go for the 4" Redhawk in 45 Colt. I've been warming up to those since they introduced them. I'd stuff it w/as big a fat, flat bullet I could handle! I agree w/"No such thing as too much"!