Welcome aboard Pat.
If you reload any of the 3 Super Redhawk chamberings will work just fine. If you do not reload I would go with a 44.
Add Hogue "Tamer" Grips. If you go with a Red Dot I would call Ruger and swap the factory 1" rings for a set of 30mm and use a 30mm Ultra Dot on it. Using a scope the 1" Rings will work fine.

You can read posts for days on this site. Lots of good information.