I hunted with an 8 3/8-inch .460 last year, and with a revolver like that, you are wasting lots of its potential without a scope. Like idling along at 5 mph in a Ferrari. I have never been a big fan of scopes on handguns, but some, like the .460 XVR are begging for it.
There are other alternatives like red-dot sights -- they don't magnify at all, just offer an alternative to iron sights. Cheating? I don't think so, you still have to hold steady to make your shot.
JMHO.