All of those loads are great for hunting. My problem with the 335 gr LBT is velocity is only 1160 fps at the accuracy point. It is a slower killer on deer so I would say a 300 gr a little faster is better.
I never tried 4227 in the .45 because I had heat problems with it in the .44. It was only accurate in a cool gun. But it worked great in the .357 max.