The .44 is fantastic for deer with about any cast boolit. The 265 gr RD with 22 gr of 296, 300 to 320 gr LBT's with 21.5 gr of 296.
Lee makes a great 310 gr mold.
These are not max loads but are the most accurate from a Ruger.
One thing Whit, other friends and I do is to use the Fed 150 primer instead of a magnum primer. Mag primers will triple group size because primer pressure will move the boolit out before a good burn is started. Each boolit moving different results in a different powder capacity for each shot.
Most boolits will shoot 1" at 50 yards or less. The little RD will do 3/4" and 1-1/4" at 100 from bags. It is a tumble lube boolit but I use Felix lube on it. I do not like Alox.
Bioman bought a new SBH Hunter, I installed an Ultra Dot on it and he was shooting 1/2" groups at 50 while sighting in using a 330 gr WLNGC boolit that I made a mold for. It uses 21 gr of 296 and I shot a 3 shot group with it at 200 yards that measured 1-5/16".
My boolits are cast from WW metal and water dropped. All are death to deer.
Here is the RD. I was hitting low so I aimed higher for the last shot.

Then my 330 gr at 200 yards during a drop test.