I tried them 10+ years ago in a .416 Taylor Encore. I was not impressed with performance or accuracy. I'm sure they've changed a lot, but there are other more established and proven bullets that will do what you want. Why take a chance?
I had a similar experience with their bullets in booth .416 and .458. I haven't used them in a revolver caliber, but they aren't the best rifle bullets. I shot a small hog with my .458 Lott many years ago, and experienced complete core separation. Now I don't know if they have improved in quality, but I am a bit skeptical.