Kyode,
I have an MGM Encore in 25 Souper (25-308) and use a load very similar to 500WE. 100 gr. Rem SPIL, Barnes 100 gr TTSX, WLR primer, and IMR-4895 and AA2520 powders. I have not pushed the "envelope" and have had excellent accuracy. The loads have accounted for a number of antelope, mulies, and whitetails.
Doc