Dan, there are some monsters to be found, especially around Interstate 70. There is great farmland along that interstate and the Deer get very well fed.
Kingfisher, I am hunting about 20 minutes from Paducah KY. I hunt just outside of a little town called Golcanda, Illinois. Golconda sits at the confluence of the Ohio River and Lusk Creek. The property I hunt is divided by Lusk Creek. Here is a link to a google Map of Golconda.
http://maps.google.com/maps?f=q&hl=en&q=Golconda,+il&ie=UTF8&z=12&om=1&iwloc=addr
I will be using a Smith & Wesson 686, 357. Its the same gun as my avatar. I put a Bushnell Trophy 2-8x32 scope on it. I will be throwing Winchester partition gold 180 gr fully jacketed hollowpoints at them. As long as I can get them in 50 yards or less I feel very confident, anything further will get to keep walking