What are your favorite loads for hunting whitetail deer with your 454?

Factory or handloads?

Handloads.

31.5 H-110 with Hornaday 300 grain XTP, Rem 7 1/2 primers

I like the 250 Hornady XTP over a medium load of 2400 and the 300 XTP over a max load of H4227

33.0gr WW296 behind a 300gr. XTP

32.5 grains of 296 with a Nosler 260 partition

26.0grs H110 (or 296)with 255gr LSWC in .45 Colt cases or 20.5grs H110 9or 296) with 300gr LSWC in .45 Colt cases.

Sorry Gary. Handloads

An old favorite whitetail load uses a standard double crimp 300gr
XTP over 27.4grs of H-4227...Rem. 7 1/2 primer...using the top crimp on the bullet. A very accurate load for bigger game has a
300gr partition over 32.0grs of H-110 and Rem 7 1/2 primer.

Both on my .454s like 300 gr Sierra JSP and 335 gr WLNGC Cast Performance bullets over W296.

Gee whiz Gary, you left me such a slam dunk opening so...

What about that "new Winchester factory load...?"

I know, it hasn't been tested that much yet, but I could not resist !

Cast Performance 335-grain WLNGC over 26.5-grains of H110 for my 4-3/4" and a Nosler 260-grain HG Partition over 34.0-grains of H110 for my 8-3/8".

I noticed no one mentioned Lil Gun. The 300gr XTPs I get. the SR Federals for sure. But I would have expected someone to load Lil Gun. No one tried it, or is not a suitable powder?

Well the Dual Bond load from Winchester is very very accurate in my FA's but it's not a handload. I'm pretty sure you can't buy the projectiles yet.

The best load in my guns was the FA 260 gr. bullet over 36 gr of H110, FA cases and Federal small bench rest primers. 5 shots one hole at 50 yards. My favorite was the old FA 300 grain bullet, why they stopped making it I'll never know, over 32 grains of H110 same primer. Fast forward to today and it is 31 of H110 under the Hornaday 300 gr. Mag bullet. It is very accurate but not quite the old 300 FA bullet.

27.9 grains of H-110 and a Barnes 250 grain xpb, 1600 fps from my srh with 7.5" barrel.

I recently loaded 7.0 grains of trail boss using a 335 grain cast bullet. Good accuracy at 50 yards. Haven't chronographed them yet but it was very mild and should be around 950 fps.

Crud! thought you said trail boss not lil gun sorry. I'm at work and the boss walked by so my attention drifted for a moment...

My load for my 454s is 300 gr XTP or Speer GD over 24 gr 2400. It is not the fastest thing out there but my revolvers group well with it. (BTW -- my 2400 is Hercules)

Do you know who is making the projectile? I know Nosler and Winchester work together on both their proprietary brands and the Combined Technology stuff, in fact the handgun and 45-70 partitions were made at the Winchester plant but I'm not sure anymore since Nosler doubled the size of their plant a couple years ago. The main reason I ask is because Nosler is up to something but they are keeping it very quiet. When I was in there last I was asking why the 45-70 partition had been discontinued and all I got was they were coming out with something new and better next year. One person speculated it may be something to compete with the FTX stuff Hornady puts in the Leverevolution ammo but he really didn't know since it's all just in house rumors at the moment. Apparently no one outside of management or those directly involved with the project are privy to the details. The cool part for us is that it will very likes carry over to their handgun line since the earlier 45-70 partition was just a .458 version of handgun partition. protected point.