I agree with azBear. I have never recovered a 44 LSWC from a deer but never shot an Elk with one. In fact, I shot a woodchuck from behind a wrecked 56 Ford front wheel (not tire) and didnt recover a bullet, but there was a clean hole through the wheel and chuck!
I find that in 41 mag,45LC, or 44 mag, LSWC's kill nicely. I don't think there's alot that would stop my ,500 with a 440LSWC at 1650fps!