While the site was down, I searched the interwebs for any suggestions of using the 250gn Barnes Casull bullet in 45colt +p loads but couldn't find any references, hence a quick write up here so others don't have to waste powder and bullets.
I wanted to use a newly acquired 45 colt RH for deer, but the 225gn Barnes bullet of choice was unavailable, but I had a good stock of the 250gn Casull bullets. Through a lot of Quickload (this load, and other loads shot in the same pistol for calibration) and a variety of 45 colt +p recipes, I worked up a ramp of H110 loading. Chrono data was 50fps slower than Quick load projections, which left me with a functional (terminal velocity limited) range of ~75 yards and poor accuracy to boot. I never finished the ramp and pulled the last load. I have the SRH 454 with me in the field this year instead.