LOL I can definitely relate to that. I do keep two loads for my big guns, a dangerous game load with hard cast and the other with jacketed bullets and your right the sighting back in is a pain, I normally count turns but it never fails I always have to spend a little time getting dialed right back in where I want it. Right now I'm in the process of building a 500 Linebaugh and it will shoot strictly hard cast and be for the biggest nastiest stuff walking.

A JHP will not penetrate as much as a quality JSP or Partition. I limit myself to broadside heart/lung shots on game so excessive penetration is not needed. With grizzlies around, I do like the fact that the 320 gr hardcast bullets from my Redhawk with break bones and give the deep penetration needed for head on shots.