I like HS 6 and use it in various calibers. In my 4" S&W 625 I'm getting 915 fps with 13.0 hrs of HS6 and a 300 gr LFNGC. Another thing that I like to do is stay with the same bullet weight in a particular gun so as to keep the same point of impact and not have to sight in every time I want to use the gun and not be confused as to what its sighted in for at that time.