I hunt deer and the occasional hog with a revolver. I much prefer iron sights but have been experimenting with RMR style red dots with excellent results in the field.
I've used 44 mag in a Ruger Bisley quite a bit, but I have had great success with heavy 44 special in an FA 97 the last couple seasons. I'll shoot to about 75 yards if everything is right but I'm much happier at 50.