Not sure how time can change pressure, it was 15 years ago that Ross wrote that article in Handloader #205, June issue, but in one paragraph he quotes from the #26 Hodgdon manual where the 45 can run a 300 gr. bullet at 1330 fps at 30,00 CUP, while it takes 35,000-38,000 CUP for the 44 to reach 1300 fps with the same bullet weight. Anway we're really splitting hairs here because when we get up to the really heavy bullets, say 340-360 gr. stuff my feeling is that its time to move up in caliber. The 480/475 caliber guns don't have the same recoil impulse & don't need to be pushed to higher pressures to perform. Using my FA 475L in Africa, my Ruger SRH 480 & recently departed Harton 480 here in Idaho with big bullets at more modest velocities makes a lot more sense, let that big, flat bullet do the work instead of the sharp recoil, your mileage may differ.

Dick