I think you would be happier with a load of 2400 and the other thing is to just use common sense with your loads and shooting.
I am glad that you are on here, and ask such a question. That right there, shows GOOD sense.
Your gun and you should be safe with the load you ask about.

W296 and H110 are supposed to be the same powder if both are made in Australia. (if I am understanding correct). Regardless of this info, powders such as these two and Enforcer. I have found as other people have, that there are pressure spikes with charges less than max or close to max. Nothing is going to beat a pressure barrel and a chronograph working together. Since most of us do not have a pressure barrel and setup for each of our handguns we just use a chronograph and watch things such as primers and case extraction. Also we can look at the case measurements. I am talking near the base of the brass. Measure a unfired case. Then fire a Factory cartridge and measure it and then measure your handload in exactly the same spot. .002 larger is getting too much pressure. Remember this is near the base,(inside)where the powder stops. At that height, measure the outside. and Also (usually) you are going to experience some difficulty in extraction.
I have used these powders in several calibers with different bullet weights. Something I have found is that for one, I need to use magnum primers.
Second with some calibers and with some bullet weights I get less than stellar results.
You are using this powder in a 44 mag, and I have found that 2400 is much better suited for this caliber than H110 or W296.

I shoot a 4 5/8 barrel length in my Ruger Bisley (44mag). Is there more muzzle flash? I have not noticed that, like I notice the recoil is greater than with a longer barrel. The one thing to remember is that the unburned powder may spit at you through the gap between the barrel and cylinder, or blast some of it out the end of the barrel, and if the wind is in your face, may even come back at you.
This is just another reason to use that magnum primer.
The other thing is that with some of the powders there is an added feature of "Low Flash". W231 has always had this, as well as some of the newer powders. AA#2 is another. And neither is suitable for your particular application.

Heat Summer temps....... With Ball Powders like W296, H110,& Enforcer. As the temps rise,,,In the 90s and above so will the pressures in the cases and guns. I live in Texas and this happens a lot. I have to switch loads or ammo. Or I can place my ammo in a baggie and put it on ice. This is necessary with Tight Cylinders, and MAX Loads. That is why I shoot different loads for summer and I try to do shooting in the morning. And I try to keep my ammo out of the Sun. Placing it in a hot gun does not help matters either. I am going to add that I have experienced this in rifles also.
See how common sense plays a big part in all this? I do not need to shoot heavy hunting loads in the middle of Summer but I can still enjoy shooting with a lighter load.
Last thing is did you get this recipe from a Handload book? Such as a Hornady bullet and the recipe from a Hornady book? It is important to use the directions from the load books. Why? Because each bullet is different. Some are longer from the crimp to the base and this will increase pressure. This really comes into play with cast bullets since there is not a lot of information on them. So be very careful of internet recipes.
The last thing is don't try to get that magic number that the book states or for that particular recipe, even if your barrel length is the same. Every gun especially "revolvers" will produce different velocities. Tim Sundles is great about publishing velocities from actual guns that he tests. Look at Buffalo Bore Ammo website.
Cylinder gaps, twist rates, worn or new barrels, polished, fire lapped, etc, etc, all make differences. If you do not have a chronograph then by all means get one and use it as often as you can to test velocities in different weather and temperatures. Cold, real cold temps will not be the same as early fall or hot weather, with several powders. We talked a little about this here, in another thread.
I know this was probably too long of a post but all I want to do is help you. Hope you don't have a headache reading all this.
What FA83ME said on the diminishing returns above Max.. Well I like to stay just a little under and be careful because who knows if ones scale or powder throw might be just a smidgen off. Even with all the lawyer stuff and manufacturers publishing safe loads. And the gunmakers using top quality materials I might add,,, Use your head.

Using a 250 grain Bullet for fun, or for a walking around the ranch or farm, and for a milder load, but yet will handle a lot of things. And that is to drop 10 grains of Unique under that 250 grain bullet. You will have a dandy load that will not be over pressure. It is enjoyable too.