The functionality of a handgun and its suitability for a certain task or situation goes far beyond its caliber. In fact I would expect the hard core handgunner to own more than one gun in their favorite caliber just for this reason. Additionally to quote Zee - "guns are cool". LOL...

In 44 Magnum I have a scoped 6" S&W 629, a Redhawk 7 1/2" with iron sights and a RSB Bisley 3 3/4" barrel belt gun. I also have a 44 Mag Contender barrel.

In 22 rimfire I have 2 S&W 17s - 1 scoped & 1 with irons. I also have a Ruger Mark II 7 1/2" with a removable red dot / irons. I probably should own a few more 22s but I haven't got there yet.

In 45 ACP I have a vintage Colt 1911 and a 5" S&W 625. Very different guns, same ammo.