I've taken around a dozen deer with a Colt and Sig .45. Inside 75 yards it does well.
A lot of bullets did poorly. I had good luck with H&G 200 gr. SWC and the best with Hornady 200 gr. XTPs.
Never shot anything other than deer. Need a hard bullet on pigs. The 200 H&G SWC might be a good one.