I haven't, but I don't see why not. Limit your shots to 75-100 yards, but more importantly, use heavy bullets like JD Jones' 310 gr. lead he developed years ago. A lot of animals larger than elk have been taken with it.
Even good ol' Kieth 240 gr. SWCs would do good, but the SSKs are better.
Penetration is the name of the game with big animals.