With the 625 (45acp) you can have the cylinder bored deeper for the 460 Rowland. Brass is available from Starline. The 460 Rowland is capable of putting your 625 past Full House Hunting 10mm ballistics. And you cannot get the ammunition to chamber in a gun not designed to take the pressure. The 460 Rowland is Slightly longer than 45acp/45 Super. Something that you can do hot rodding the 45acp and 45 Super. I had my cylinder bored 20 years ago. No idea what it would cost today, but I can not imagine it being much over $125.
You can seat bullets longer in a Rowland 625 than in a G21 or 1911 conversion leaving more powder space. The 625 will handle bullets with a huge meplat that will not feed in a semi auto. Another good point.
I have not worked with my 460 Rowland Conversion in several years. Today we have Power Pistol powder which should be a great choice. I believe I may have been using Blue Dot years ago.
The 460 Rowland is something to think about.

Bob