I've shot deer and hogs with the .44 Mag. Speer 200 gr. jacketed magnum hollowpoint out of a 10" Contender and 5" 629. Full penetration and all DRT or within 10 yds.
My usual .44 load for over 35 years has been the Sierra 240 JHC, but it never killed anything any faster than those 200 gr. Speers.