Randy I used to have an Xframe in the 500 S&W w/ 8 3/8" barrel. SO I can only talk about size and weight. +1 on the suggestion of getting an XFrame from the performance center if you go with a S&W. But the BFR is very accurate, and the weight is comparable. S&W 72oz and the BFR is 74oz
If you like double actions, and the grips, then the Smith is it. But if you want a Single action I would look no further than the BFR.
Remember you can go one of two ways on the grip. The Rubber or the new Bisley version Magnum Research has designed.
Now +1 on Chances post. In order to get the most from the 460 it needs to be run fast. Put a Good Scope on the pistol. I would also suggest using Jacketed bullets. Invest in a good pair of shooting gloves.

Charles
If you want the rubber grip you can find them at reduced prices. Buds gun shop had some in the 900.00 range recently. (If they still have them).