Real life testing on my 2000+ deer show 150/165 BTs usually go all the way through. 165Xs never stay in a deer. 150 Horn. SPs frequently stay in. Internal damage in the 2-3 1/2" range on the Noslers and about 1/2-2/3 as much with the X.
The big surprise is the little 115 gr. Lehigh Chaos. Never had the base stay in a deer out to 400, but a few pedals do, and if you experiment with powders you can make them shoot the same as 150s at least to 400.+ Internal damage around 2 1/2" for the base,1/2" for the pedals.