On my FA .475 L I have a rear V sight and green & orange fiber optic front sights. I have a Ruger .44 with rear V and front gold bead.
The gold bead works good in good light, but the fiber optics do much better in dimmer light. Used the orange on my rhino at 30 yds (good against the dark skin) and the green on my lion at 30 yds (good contrast with the light brown skin).
The gold bead does allow a little finer "picture" at extended range, but I've used the fiber optics out to 75 yds. on deer without problems.