The problem with using the shorter rounds is the immense (relatively speaking) distance the bullets have to travel unsupported from the case mouth to the chamber's throat. Unlike the 357/38 and the 44 Magnum/Special, which have only .1" of jump, the 460/45 has about .5" to travel unsupported. That's not to say they'll never shoot accurately.

Someday, when I have enough free time again, I'm going to test how much the difference in length affects accuracy.