Not saying that this is not an option. But I shot a deer this year with a 44 mag Model 69 S&W and a pretty hot 180 XTP.
Square shoulder shot at 20 yds. That deer ran over 400 yds.

After that I went back to my 45 Colt and the old 250 XTP and the 44 mag 240.

Sticking with the bigger stuff for hunting.

Save the others for wild dogs and devil worshipers.