The Hodgdon web site shows up to 45.5 gr of IMR 4895 but I had sticky extraction around 45 gr. and the load was not near as accurate as the 43.0 gr load. That gives you a little wiggle room above 43 gr.to experiment with. I hunt and shoot silhouette with my Striker and I choose accuracy over velocity .At 43 gr. the gun shoots all 4 of the bullets mentioned very well and is very consistent.