Just hang on tight with both hands...and use a very good scope. The muzzle brake is essential, at least for me. Hard a hard time early on with my bipod, pulled the sling screw right through the rynite stock (now I moved to a barrel-clamped mount for my bipod, but haven't tested that much yet for accuracy impact).
I don't reload, but had some 235 gr Hawk bullets loaded up, and feel very confident out to 200+ yards without much drop...and of course the energy is phenomenal way beyond that range, so long as you can place the bullet.
Someday I hope to take that barrel to Africa and shoot something REALLY big. My whole purpose with the 405 was to have a straight-walled cartridge that would work in the Contender and reach deer as far as possible across the cornfield (Illinois restrictions on cartridge style).