SC,
There's one item every handgun hunter goes through....carrying your rig out in the field.
Holsters!
1. Hip holster drags your pants down half the time?
2. Side shoulder holster makes for a week of swore ribs.
3. Backpacking in to your stand may upset some Game/Forrest Ranger?
Having most single shot pistols made in the past 30 years and hunted with some...here's my suggesting: Keep the over all length/width with or without scope as short as possible and carry it chest mounted Bandoleer! Really makes for a healthy body the following week after the hunt!
Guess all my bantering points to middle grip, maybe?
WolfTrap