For those who have been looking at the 454 and 480 Ruger I thought I would threw these numbers out.

I looked at the KO factors and the Foot Pounds calculator when comparing the 480 and the 454. The numbers were both impressive to say the least. My conclusion is that if you put your bullet in the right spot, positive results will follow suit. You can split hairs, but they both sport good numbers IMHO.

KO:
480 Ruger w 325gr at 1500 = 33
480 Ruger w 400gr at 1200 = 33 hmmmmmm

454 w 240gr at 1800 = 28
454 w 300gr at 1600 = 31

Energy:
325gr at 1500 = 1624
300gr at 1600 = 1706
240gr at 1800 = 1727

All three fps stats are pretty much comparable IMHO. Particularly sense you are taking bullet diameter out of the equation. In short, I don't think your game will ever know the difference. LOL